Advance on Controlled-and Sustained-release Dosage Forms Remaining Floating in Stomach with Prolonged Gastric Resident Time

QU Li1; 2; WANG Zhi-min1; TONG Yan1

您当前的位置：

首页 >

文章列表页 >

Advance on Controlled-and Sustained-release Dosage Forms Remaining Floating in Stomach with Prolonged Gastric Resident Time

更新时间：2024-01-04

- Advance on Controlled-and Sustained-release Dosage Forms Remaining Floating in Stomach with Prolonged Gastric Resident Time
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 12, Issue 7, Pages: 66-70(2006)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2006
- 稿件说明：
移动端阅览
QU Li1, 2, WANG Zhi-min1, et al. Advance on Controlled-and Sustained-release Dosage Forms Remaining Floating in Stomach with Prolonged Gastric Resident Time[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 66-70.
DOI：

QU Li1, 2, WANG Zhi-min1, et al. Advance on Controlled-and Sustained-release Dosage Forms Remaining Floating in Stomach with Prolonged Gastric Resident Time[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(7): 66-70. DOI：

摘要

综述了胃滞留漂浮型缓控释给药系统的释药原理、漂浮性能的影响因素及制剂质量评价等方面的内容。根据近十年来国内外文献报道介绍胃滞留漂浮型缓控释制剂的研究进展情况

阐述了制剂主要适用于在胃部或者小肠上部有特定吸收或具有专属性治疗等药物

通过延长药物在胃肠道内的滞留时间来提高药物的生物利用度和有效性;因此该制剂具有广阔的发展前景。

Abstract

This paper reviews the theory of releasing drugs on floating sustained-release dosage forms for gastric retention and influential factors of floating and evaluation on dosage quality control.According to the development on the dosage forms in recent decades

such retention systems are important for drugs that are best for absorption in the stomach or upper the intestine as well as for controlling release of the drugs having site-specific absorption limitations.Retention of drug delivery system in stomach prolongs overall gastrointestinal transit time

thereby resulting in improved bioavailability and efficiency for some drugs.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰