HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan

ZHAO Xian-hong1; LI Xiang-ri1; YUAN Yong-sheng2; ZHOU Yu-xin2

您当前的位置：

首页 >

文章列表页 >

HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan

更新时间：2024-01-04

- HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 11, Issue 2, Pages: 13-15(2005)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2005
- 稿件说明：
移动端阅览
ZHAO Xian-hong1, LI Xiang-ri1, YUAN Yong-sheng2, et al. HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(2): 13-15.
DOI：

ZHAO Xian-hong1, LI Xiang-ri1, YUAN Yong-sheng2, et al. HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(2): 13-15. DOI：

摘要

目的:建立藿香正气丸(大蜜丸)中厚朴酚、和厚朴酚的含量测定方法。方法:采用高效液相色谱法

以ZORBAX SB-C18色谱柱(5μm

4.6mm×150mm

SN:USCL012593)

乙腈-水(68∶32)为流动相

流速为1.0mL/min

检测波长为294nm

室温25℃。结果:厚朴酚在0.18μg～3.5μg范围内呈良好的线性关系

该方法平均回收率为98.5%

RSD为1.5%；和厚朴酚在0.11μg～2.2μg范围内呈良好的线性关系

该方法平均回收率为101.8%

RSD为2.7%。结论:本方法简单、灵敏度高

可用于藿香正气丸(大蜜丸)中厚朴酚、和厚朴酚的含量测定。

Abstract

Objective:To establish a method for determining Magnolol and Honokiol in the Huoxiang Zhengqi Wan. Method:An HPLC method was designed

which was performed under the following conditions:Zorbax sb-C18 column (4.6mm×150mm

5μm) as the chromatographic column

acetonitrile-water(68∶32) as the mobile phase at a flow velocity of 1.0mL/min

and the wavelength of 294nm as the detecting wavelength. Results:The calibration curves were linear in the range of 0.18 μg～3.5 μg magnolol and 0.11 μg～2.2 μg honokiol. The RSD was 1.5%(n=5) and 2.7%(n=5)

and the average recovery was 98.5% and 101.8%

respectively. Conclusion:This HPLC method is easy and accurate

and can be used as one of the methods for controlling the quality of the Huoxiang Zhengqi Wan.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Principal,Assistant,Compleaent,Guide Compatibility of Banxiahoupo Decoction on Contents of Honokiol and Magnolol

Grade Evaluation of Magnoliae Officinalis Cortex Processed with Ginger Juice Based on Relative Quality Constant

Determination of magnolol and honokiol in XIANGSHA YANGWEI GRANULES by RP-HPLC

Determination of Hesperidin,Eugenol,Honokiol and Magnolol in Shenxiang Yangwei Capsule by HPLC

HPLC for quantification of glycyrrhizic acid, 6-gingerol, honokiol and magnolol in Wenfei Zhike Capsule

Related Author

XU Qun1

OUYANG Zhen2

CHANG Yu2

FU Dong-sheng3

KONG Ling-dong1

Quan ZHANG

Wen-guang JING

Zhe DENG

Related Institution

China National Traditional Chinese Medicine Co. Ltd.

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College

Henan Puyang Institute for Food and Drug Control

School of Pharmacy，Shanxi Medical University

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰