Experimental Studies of Fumai Ⅰ on Thiggered Activity Induced by Stress in Guinea Pig in Vivo
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Experimental Studies of Fumai Ⅰ on Thiggered Activity Induced by Stress in Guinea Pig in Vivo
Chinese Journal of Experimental Traditional Medical FormulaeVol. 10, Issue 3, Pages: 33-36(2004)
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Published:2004
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LI Wen-hong, ZHOU Qing-gan, LIAO Qun, et al. Experimental Studies of Fumai Ⅰ on Thiggered Activity Induced by Stress in Guinea Pig in Vivo[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 33-36.
DOI:
LI Wen-hong, ZHOU Qing-gan, LIAO Qun, et al. Experimental Studies of Fumai Ⅰ on Thiggered Activity Induced by Stress in Guinea Pig in Vivo[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 33-36.DOI:
Experimental Studies of Fumai Ⅰ on Thiggered Activity Induced by Stress in Guinea Pig in Vivo
Objectives:To observe the protective effects and mechanism of Fumai Ⅰ on arrhythmias and myocardial injury induced by stress. Methods: Chronic stress guinea pig model was established by footshock during a long period
arrhythmias was induced by Isoprenaline
epicardial Monophasic action potential (MAP) and ECG were detected synchronously
the activities of LDH
CK
NOS and the content of NO in myocarditis were measured. Results: Fumai Ⅰ can reduce the incidences of arrhythmias and triggered activity
the activity of LDH
NOS and the content of NO
increased the activity of CK in myocardium. Conclution:Fumai Ⅰ has a protective effect on arrhythmias and myocardial injury induced by stress.
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State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
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