Protective Effects of JWYPFS on Lung Injury Cassed by Passive Smoking in Rats

DENG Yun; ZHANG Jin; WANG Li-jin; MEI Ren-biao; SUN Shan-cai; XU Guang-xu

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Protective Effects of JWYPFS on Lung Injury Cassed by Passive Smoking in Rats

更新时间：2024-01-04

- Protective Effects of JWYPFS on Lung Injury Cassed by Passive Smoking in Rats
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 10, Issue 3, Pages: 21-23(2004)
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- Published：2004
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DENG Yun, ZHANG Jin, WANG Li-jin, et al. Protective Effects of JWYPFS on Lung Injury Cassed by Passive Smoking in Rats[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 21-23.
DOI：

DENG Yun, ZHANG Jin, WANG Li-jin, et al. Protective Effects of JWYPFS on Lung Injury Cassed by Passive Smoking in Rats[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 21-23. DOI：

摘要

目的观察加味玉屏风散对被动吸烟大鼠肺组织损伤的影响。方法以烟熏法制备被动吸烟大鼠模型

以病理切片法、生化分光光度等法分别观察加味玉屏风散对肺组织病理形态学、肺平均动脉压以及对肺组织中一氧化氮(NO)含量、一氧化氮合酶(NOS)活性、超氧化物歧化酶(SOD)活性、丙二醛(MDA)含量的影响。结果加味玉屏风散可以明显改善模型大鼠的肺组织病理学改变

降低肺平均动脉压

并提高肺组织中NO含量、NOS活性、SOD活性以及降低MDA含量。结论加味玉屏风散对被动吸烟大鼠所致肺损伤具有一定的保护作用。

Abstract

AIM:To study the protective effects of JWYPFS on lung in jury caused by passive smoking in rats. METHODS: The model of passive smoking rat was caused by cigarette smoke. The influence of JWYPFS on pathomorphology of lung tissue

mean arterial pressure of lung

activity of NOS

SOD and content of No

MDA in lung tissue were observed. Results: JWYPFS obviously improved the pathomorphology of lung tissue

decreased the mean arterial pressure of lung

increased the content of NO

the activity of NOS and SOD

decreased the content of MDA in lung tissue. Conclusion:JWYPFS had the protective effects on lung in jury of rats caused by passive smoking.

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