Experimental Research of Yangxue Tiaogan Fang on Neuroendocrino-Immunological Effect of First Aging Female Rats

Yuan Jing; CHEN Quan-zhu; HOU Zheng-ming; LIU Xian-hua; ZHANG Fu-qing

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Experimental Research of Yangxue Tiaogan Fang on Neuroendocrino-Immunological Effect of First Aging Female Rats

更新时间：2024-01-04

- Experimental Research of Yangxue Tiaogan Fang on Neuroendocrino-Immunological Effect of First Aging Female Rats
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 11, Issue 1, Pages: 34-36(2005)
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- Published：2005
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Yuan Jing, CHEN Quan-zhu, HOU Zheng-ming, et al. Experimental Research of Yangxue Tiaogan Fang on Neuroendocrino-Immunological Effect of First Aging Female Rats[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(1): 34-36.
DOI：

Yuan Jing, CHEN Quan-zhu, HOU Zheng-ming, et al. Experimental Research of Yangxue Tiaogan Fang on Neuroendocrino-Immunological Effect of First Aging Female Rats[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(1): 34-36. DOI：

摘要

目的:探讨养血调肝方对初老雌性大鼠神经内分泌免疫方面的影响。方法:选用自然衰老雌性大鼠

观察给予养血调肝方后用放射免疫分析法检测血浆促肾上腺素皮质激素(ACTH)

β-内啡肽(β-END)

血清雌二醇(E2)

睾酮(T)

促卵泡激素(FSH)

三碘甲状腺原氨酸(T3)甲状腺素(T4)促甲状腺素(TSH)白细胞介素-II(IL-2)

肿瘤坏死因子(TNF)的含量

并观察肾上腺、卵巢和胸腺脏器指数的变化。结果:与初老对照组比

养血调肝方组的上述指标均有明显改善

且与六味地黄汤组比无显著差异。结论:养血调肝方具有调节神经、内分泌、免疫的作用。

Abstract

AIM:To study the effect of Yangxue Tiaogan Fang(YXTGF) on neuroendocrino-Immunological in first aging female rats.METHODS:In the first aging female rats with YXTGF and the same aged control

the following determinations

including adrenocorticotropine (ACTH)

β-endorphin (β-END)

estradiol (E2)

testosterone(T)

follicle stimulating hormone (FSH)

triiodothyronine(T3)

thyroxine(T4)

thyroid stimulating hormone (TSH)

interleukin-II(IL-2)

tumour necrosis factor (TNF) in the blood

were carried out by radioimmunoassay and the weight indexes of adrenal

ovary and thymus were examined.RESULTS:The indexes of YXTGF group were improved respectively

and there was no significant difference between YXTGF group and Liuwei Dihuang Tang (Positive drug)group.CONCLUSION:It is suggested that YXTGF may regulate neuroendocrino-Immunological function.

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