Effect of Tablet Extracted from Rhubarb on Hyperinsulinemia in Simple Obese Rats
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Effect of Tablet Extracted from Rhubarb on Hyperinsulinemia in Simple Obese Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 8, Issue 6, Pages: 29-31(2002)
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Published:2002
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Effect of Tablet Extracted from Rhubarb on Hyperinsulinemia in Simple Obese Rats[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(6): 29-31.
DOI:
Effect of Tablet Extracted from Rhubarb on Hyperinsulinemia in Simple Obese Rats[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(6): 29-31.DOI:
Effect of Tablet Extracted from Rhubarb on Hyperinsulinemia in Simple Obese Rats
Aim:To study effect of the tablet extracted from rhubarb on hyperinsulinmia in simple obese rats.Methods:The simple obese rats with hyperinsulinmia were randomly divided into two groups:experimental group was composed of eight rats
administrated with tablet extracted from rhubarb
0.25g/100gb.w/day
control group:eight rats
administrated with N.S.The serum insulin and peptide C were detected by radioimmunoassay
the serum TNF-α by ELISA.Results:After administration of tablet extracted from rhubarb for one month
the body weight in experimental rats was obviously reduced
at the same time
the level of insulin
peptide C and TNF-α remarkably lowered.There is a positive relationship between the serum insulin and TNF-αlevel.Conclusion:The tablet extracted from rhubarb demonstrated significant effects on reducing body weight and lowering the serum insulin level in hyperinsulinmia in simple obese rats
which may be contributed to the decrease of TNF-α level