Effects of Capsule Assemble Flavones of Fortune's Drynaria Rhizome on the Experimental Osteoporosis in Rat and Analgesia Action in Mouse
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Effects of Capsule Assemble Flavones of Fortune's Drynaria Rhizome on the Experimental Osteoporosis in Rat and Analgesia Action in Mouse
Chinese Journal of Experimental Traditional Medical FormulaeVol. 10, Issue 5, Pages: 31-34(2004)
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Published:2004
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LIU Jian-gang1, XIE Yan-ming1, ZHAO Jin-ning1, et al. Effects of Capsule Assemble Flavones of Fortune's Drynaria Rhizome on the Experimental Osteoporosis in Rat and Analgesia Action in Mouse[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(5): 31-34.
DOI:
LIU Jian-gang1, XIE Yan-ming1, ZHAO Jin-ning1, et al. Effects of Capsule Assemble Flavones of Fortune's Drynaria Rhizome on the Experimental Osteoporosis in Rat and Analgesia Action in Mouse[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(5): 31-34.DOI:
Effects of Capsule Assemble Flavones of Fortune's Drynaria Rhizome on the Experimental Osteoporosis in Rat and Analgesia Action in Mouse
Objective To investigate the effects of assemble flavones of Fortune's drynaria rhizoma on animal bone mineral density
phasma calcium and phosphorus
and on analgesia action.Methods Wistar rat and Kunming mouse were used as experimental animals. Osteoporosis was induced by orally given retinoic acid(70 mg·kg-1·d-1) to the rats for 14 dasy. For evaluation of analgesia action
body wresting was induced by vinegar id injection in the mice
and hot plate method(55℃) of mouse was employed. Results Bone mineral density and plasma calcium were significantly increased for the dose groups of Fortune's drynaria zhizoma compared with the control(P<0.05).Analgesia action evaluated by vinegar induced and heat induced pain was also significant compared with the control(P<0.05).Conclusion The assemble flavones of Fortune's drynaria rhizoma have the functions of elevating blood calcium
increasing bone mineral density and analgesia action.
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School of Pharmacy, Guangxi University of Chinese Medicine
Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Guangxi University of Chinese Medicine
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The First Affiliated Hospital of Guangxi University of Chinese Medicine
TCM Hospital Xianju of the Second Affiliated Hospital of Zhejiang Chinese Medical University