Study on Effect of Fuzheng Quxie Chinese Drugs on Monkey of SIV Infection Moden

XU Shuling1; GUAN Chong-fen1; WENG Xin-yu1; WU Xiao-xian2; LU Yao-zeng2

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Study on Effect of Fuzheng Quxie Chinese Drugs on Monkey of SIV Infection Moden

更新时间：2024-01-04

- Study on Effect of Fuzheng Quxie Chinese Drugs on Monkey of SIV Infection Moden
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 9, Issue 1, Pages: 42-44(2003)
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- Published：2003
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XU Shuling1, GUAN Chong-fen1, WENG Xin-yu1, et al. Study on Effect of Fuzheng Quxie Chinese Drugs on Monkey of SIV Infection Moden[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(1): 42-44.
DOI：

XU Shuling1, GUAN Chong-fen1, WENG Xin-yu1, et al. Study on Effect of Fuzheng Quxie Chinese Drugs on Monkey of SIV Infection Moden[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(1): 42-44. DOI：

摘要

扶正祛邪中药复方“艾克冲剂”对猴SIV感染模型(SAIDS)治疗作用。方法:利用SIVmac病毒液静脉接种恒河猴造成猴艾滋病实验模型

流式细胞仪测定感染及治疗动物外周血CD+4细胞、CD+8细胞数及CD+4CD+8比值

并以MTT法观察T、B细胞对有丝分裂原诱导分化增殖反应。结果:艾克冲剂能提高CD+4细胞百分数及CD+4CD+8比值

并能促进T、B淋巴细胞增殖。结论:扶正祛邪中药艾克冲剂能够提高、改善SIVmac感染动物免疫功能。

Abstract

Objective:To Investigate the effect of Lyke Granule on simian immunodeficiency Virus(SIV) infection model. SAIDS model were used. Using monoclonal antibody label on CD+4 and CD+8 cells in PBMC with direct immunofluorescence

the percentage was analyzed by flow cytometry and analyzed CD+4/CD+8 ratio. T and B cells proliferation induced by mitogens was defected before treatment and after treatment with Lyke Granule. Results indicate that Lyke Granule enhanced the proliferation of T and B cells induced by motogen

CD+4 T cells were increased in PBMC and CD+4/CD+8 were changed.

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