Studies on The Pharmacological Effect of Qianhu Ketan Tang

WU Hao; ZHOU Chao-fan; LU Ai-ping

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Studies on The Pharmacological Effect of Qianhu Ketan Tang

更新时间：2024-01-04

- Studies on The Pharmacological Effect of Qianhu Ketan Tang
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 9, Issue 6, Pages: 25-26(2003)
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- Published：2003
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WU Hao, ZHOU Chao-fan, LU Ai-ping. Studies on The Pharmacological Effect of Qianhu Ketan Tang[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(6): 25-26.
DOI：

WU Hao, ZHOU Chao-fan, LU Ai-ping. Studies on The Pharmacological Effect of Qianhu Ketan Tang[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(6): 25-26. DOI：

摘要

目的:探讨前胡咳痰汤的药理作用。方法:分别用氨水及组胺与乙酰胆碱吸入造成小鼠咳嗽与哮喘的模型

给予前胡咳痰汤及阳性对照药进行治疗

利用酚红腹腔注射观察其祛痰作用。以流感病毒滴鼻法造成模型

观察了本方的抗病毒作用。结果:1前胡咳痰汤大、小剂量组均能明显延长小鼠咳嗽潜伏期。2本方的大剂量组酚红排泌量高于空白对照组。3本方大剂量组引喘潜伏期较空白对照组明显延长

大剂量组较氨茶碱组引喘潜伏期稍有延长。4前胡咳痰汤大剂量组肺指数比病毒组减轻。结论:前胡咳痰汤有明显的止咳

化痰

平喘及抗病毒作用。

Abstract

Objective:To explore the pharmacological effect of Qianhu Ketan Tang(QKT).Methods:Mouse model of cough and model of asthma were established by using ammonia and histamine with acetycholine inspiration accordingly. We investigated effects of OKT and a positive drug on expectorant by using the model with intraperitoneal injection of phenolsulfonphthalein. The anti-virus action of QKT was evaluated by a model of virus infection induced by influenzavirus nosedrop.Results:1 QKT high dose group and QKT low dose group can prolong the cough incubation period in mice. 2 QKT high dose group can increase the excretion of phenolsulfonphthalein. 3 QKT high dose group can prolong the sathma incubation period in mice. 4 The lung weights of QKT high dose group are lower than that of model group. Conclusion:QKT have good effect of cough suppression

expectorant and relieving asthma

and it can protect lung from attack of virus.

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