Bupleurum root and Scutellaria root is the core paired-component of the Minor Chaihu decoction.In the experiment we observed the effects of anti-febrile of the Bupleurum root and Scutellaria root mingled decoction and separated decoction on the fever induced by LPS intraperitoneally injected at the dose of 20μg/kg and 80μg/kg

respectively.Both of the decoctions orally administrated can significantly inhibited the fever induced by LPS at both doses ( P<0.05 or 0.01)at the dose of 10g/kg

and there is no significance between the both decoctions.But analyzing the effects comprehensively

we found that the mingled decoction presented the anti-febrile effet earlier than the separated decoction

and indicated a better efficacy in trend.