New Progression of Chemical Component and Pharmacological Studies of Radix Bupleuri

SHI Qing; NIE Shu-qin; HUANG Lu-qi

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New Progression of Chemical Component and Pharmacological Studies of Radix Bupleuri

更新时间：2024-01-04

- New Progression of Chemical Component and Pharmacological Studies of Radix Bupleuri
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 8, Issue 5, Pages: 53-56(2002)
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- Published：2002
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SHI Qing, NIE Shu-qin, HUANG Lu-qi. New Progression of Chemical Component and Pharmacological Studies of Radix Bupleuri[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(5): 53-56.
DOI：

SHI Qing, NIE Shu-qin, HUANG Lu-qi. New Progression of Chemical Component and Pharmacological Studies of Radix Bupleuri[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(5): 53-56. DOI：

摘要

介绍了近十年来柴胡属植物化学成分及主要化学部位药理研究新进展。在柴胡属植物中新发现柴胡皂甙K、I、M、N、Q、T。通过主要化学部位的药理研究发现柴胡皂甙在抑制胰蛋白酶、调节免疫、治疗肾病及失眠方面的作用或深入机理

并对柴胡多糖进行了进一步分离研究

提出了可能活性部位

为其在胃粘膜保护和免疫调节方面新药研究提供基础。柴胡提取对物对腺苷酸环化酶(AC)的双重作用使柴胡的应具有新的前景。

Abstract

It was introduced for new progression of chemical component and pgarmacological studies on main chemical fractions of Radix Bupleuri in recent ten years.Saikosaponin k

were discovered lately.Through the pharmacological studies on main chemical fractions

saikosaponin could inhibite the activity of trypsin

regulate immunity

and treat nephrosis and insomnia.The mechanisms of these actions were studied.Through farther separated studies of polysaccharide of Radix Bupleuri

the possible active fractions were brought forward.It provides the background for the new drug study of gastric mucosa protection and immunoloregulation.New prospect was showed for the application of Radix bupleuri because of double action to adenylate cyclase (AC) of the extracts of Radix Bupleuri.

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Related Author

WANG Kai

QU Zhenni

BI Yu

SHI Dianhua

DAI Yanpeng

CHEN Lin

JI Baoyu

PEI Lixin

Related Institution

Shandong Academy of Chinese Medicine

Shandong University of Traditional Chinese Medicine

Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-yao

Henan Provincial Ecological Planting Engineering Technology Research Center of Authentic Medicinal Materials

Henan Key Laboratory of Traditional Chinese Medicine Resources and Chemistry

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