Experimental Studies on Protective Effect of the Rhubarb and Leech etc. Remedy to The Rats with Kidney Subtotal Excision
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Experimental Studies on Protective Effect of the Rhubarb and Leech etc. Remedy to The Rats with Kidney Subtotal Excision
Chinese Journal of Experimental Traditional Medical FormulaeVol. 10, Issue 1, Pages: 31-34(2004)
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Published:2004
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ZHANG Cui1, KANG Guang-sheng2, LIU Wei1. Experimental Studies on Protective Effect of the Rhubarb and Leech etc. Remedy to The Rats with Kidney Subtotal Excision[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(1): 31-34.
DOI:
ZHANG Cui1, KANG Guang-sheng2, LIU Wei1. Experimental Studies on Protective Effect of the Rhubarb and Leech etc. Remedy to The Rats with Kidney Subtotal Excision[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(1): 31-34.DOI:
Experimental Studies on Protective Effect of the Rhubarb and Leech etc. Remedy to The Rats with Kidney Subtotal Excision
Objective:To study the Rhubarb and Leech etc.remedy protection to the chronic renal failure(CRF) model of rats with kidney excision.Methods:The model of rats with 5/6 kidney excision were used.The rats were divided into the unexcised-operation group
the most kidney excised model group
the coated aldehyde oxystrach group
the Shensuaining group and the high
middle and low dose Rhubarb and Leech groups.The tumor necrosis factor (TNF-α) by ELISA
the 24 hrs' urine proteins
blood urea nitrogen(BUN) and serum creatinine(Scr) in the rats were monitored.Results:The Rhubarb and Leech etc.remedy could reduce the urine proteins
decline the tumor necrosis factor
blood urea nitrogen(BUN) and serum creatinine (Scr).Especially
the low dose group had the significant effect
which had the significant difference from the model.Conclusion:The Rhubarb and Leech etc.remedy could protect the kidney subtotal excision rats and decrease the renal injury.