Protective Effects of Tatal Saponin of and Notoginsenosides on the Hypoxia induced damage of Cultured Vascular Endothelial Cells in
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Protective Effects of Tatal Saponin of and Notoginsenosides on the Hypoxia induced damage of Cultured Vascular Endothelial Cells in
Chinese Journal of Experimental Traditional Medical FormulaeVol. 8, Issue 1, Pages: 34-37(2002)
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Published:2002
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YAN Yanfang1, ZHANG Zhuang1, SUN Sulun1, et al. Protective Effects of Tatal Saponin of and Notoginsenosides on the Hypoxia induced damage of Cultured Vascular Endothelial Cells in [J]. Chinese journal of experimental traditional medical formulae, 2002, 8(1): 34-37.
DOI:
YAN Yanfang1, ZHANG Zhuang1, SUN Sulun1, et al. Protective Effects of Tatal Saponin of and Notoginsenosides on the Hypoxia induced damage of Cultured Vascular Endothelial Cells in [J]. Chinese journal of experimental traditional medical formulae, 2002, 8(1): 34-37.DOI:
Protective Effects of Tatal Saponin of and Notoginsenosides on the Hypoxia induced damage of Cultured Vascular Endothelial Cells in
The model of hypoxia induced damage in cultured vascular endotheliocyte cells was set up in vitro
toxicity was tested by MTT assay
effect was evaluated by classic pharmacodynamic criteria Trypan blue stain
lactate dehydrogenase (LDH) release
and MTT assay. The results showed the mortality rate and LDH release were significantly decreased to compare with the damaged group
(P<0.001)
and the cell survival rate was significantly increased (P<0.001)in the protective groups of total saponins of Panax notoginseng and notoginsenoside Rb1
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Related Institution
Cancer Institute (Xuzhou) of Southeast University
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Anhui Provincial Key Laboratory of Chinese Medicinal Formula,Anhui University of Chinese Medicine