Studies of Niaopinkang for Inhibiting Urination and Pharmacokinetics in Mice and Rats
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Studies of Niaopinkang for Inhibiting Urination and Pharmacokinetics in Mice and Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 6, Issue 6, Pages: 18-20(2000)
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Published:2000
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YUAN Wen-peng2, ZHANG Shuo-geng1, SHEN Xin3, et al. Studies of Niaopinkang for Inhibiting Urination and Pharmacokinetics in Mice and Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, 6(6): 18-20.
DOI:
YUAN Wen-peng2, ZHANG Shuo-geng1, SHEN Xin3, et al. Studies of Niaopinkang for Inhibiting Urination and Pharmacokinetics in Mice and Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, 6(6): 18-20.DOI:
Studies of Niaopinkang for Inhibiting Urination and Pharmacokinetics in Mice and Rats
Niaopinkang at the doses of 5~20 g/kg decreased the times and volume of urination in the mice and rats receiving ip water or furosemide. The duration of action after oral administration is from 0.5 to 7h. The behavior of Niaopinkang was showed by two-compartment model using residual rate and effect-dose relationship. Results indicated that the apparent t1/2 and effect-dose t1/2 were 5.428 h and 5.847 h