Effects of Bu Yang Huan Wu Decoction and its Active Fraction on Excitatory Amino Acid of Brain Tissue After Cerebral Ischemia and Reperfusion in Gerbils
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Effects of Bu Yang Huan Wu Decoction and its Active Fraction on Excitatory Amino Acid of Brain Tissue After Cerebral Ischemia and Reperfusion in Gerbils
Chinese Journal of Experimental Traditional Medical FormulaeVol. 7, Issue 6, Pages: 24-27(2001)
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Published:2001
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DENG Chang-qing1, DENG Yi-hui1, HE Fu-yang1, et al. Effects of Bu Yang Huan Wu Decoction and its Active Fraction on Excitatory Amino Acid of Brain Tissue After Cerebral Ischemia and Reperfusion in Gerbils[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(6): 24-27.
DOI:
DENG Chang-qing1, DENG Yi-hui1, HE Fu-yang1, et al. Effects of Bu Yang Huan Wu Decoction and its Active Fraction on Excitatory Amino Acid of Brain Tissue After Cerebral Ischemia and Reperfusion in Gerbils[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(6): 24-27.DOI:
Effects of Bu Yang Huan Wu Decoction and its Active Fraction on Excitatory Amino Acid of Brain Tissue After Cerebral Ischemia and Reperfusion in Gerbils
To compare the effects of Bu Yang Huan Wu Deciction (BYHWD) and its active fraction on brain tissue following cerebral ischemia and reperfusion
Ceredral ischemia model in gerbils was indcued by ligating bilateral common carotid artery.The contents of glutamate (Glu)
aspirate (Asp) and γ-amino butyric acid
glycine in brain tissue were determined after cerebral ischemia for 15min followed by reperfusion for 48 hours.Results showed the contents of Glu
Asp and γ-aminobutyric acid in brain tissue were markedly enhanced after cerebral ischemia for 15min.BYHWD decreased the contents of Glu in brain tissue remarkably;its active fraction reduced the contents of both Glu and Asp in brain tissue remarkably.The contents of Glu and Asp in brain tissue were remarkably increased after cerebral ischemia for 15min followed by reperfusion for 48 hours
BYHWD decreased the contents of Glu in brain tissue significantly
its active fraction reduced the contents of both Glu and Asp in brain tissue remarkably.
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