Preparation of Gel in Rectal Administered——Selection of Excipients and Osmotic-promoting Regents
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Preparation of Gel in Rectal Administered——Selection of Excipients and Osmotic-promoting Regents
Chinese Journal of Experimental Traditional Medical FormulaeVol. 7, Issue 2, Pages: 7-11(2001)
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Published:2001
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Feng Yi, Shi Zhi-ying, Xu Lian-ying. Preparation of Gel in Rectal Administered——Selection of Excipients and Osmotic-promoting Regents[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(2): 7-11.
DOI:
Feng Yi, Shi Zhi-ying, Xu Lian-ying. Preparation of Gel in Rectal Administered——Selection of Excipients and Osmotic-promoting Regents[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(2): 7-11.DOI:
Preparation of Gel in Rectal Administered——Selection of Excipients and Osmotic-promoting Regents
The concentration of ephedrine and pseudoephedrine in rabbit's blood were determined by HPLC method after rectal administered with xiao'er xiaochuan gel.The rectal administered was used by the venous intubation on rabbit's rectal mesentery in vivo. The excipients and osmotic-promoting regents were screened by the blood concentration of above markers.The optimized prescription were made up of oleic acid and azone as osmotic-promoter