TANG Qing-fa, XIE Ying, CHEN Fei-long, et al. Existing form of Amygdalin in Bitter Almond and Influence Factors[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 107-109.
DOI:
TANG Qing-fa, XIE Ying, CHEN Fei-long, et al. Existing form of Amygdalin in Bitter Almond and Influence Factors[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 107-109. DOI: 10.11653/syfj2013080107.
Existing form of Amygdalin in Bitter Almond and Influence Factors
Objective: To evaluate the existing form of amygdalin in bitter almond and the influence of temperature and acid-base on isomerization of amygdalin. Method: Use high performance liquid chromatography (HPLC) to determine the peak area of D-amygdalin and L-amygdalin in different decocting temperature
and use this method qualitatively investigate the influence of acid-base on isomerization of amygdalin monomer. Result: Amygdalin in Semen Armeniacae Amarum in different temperatures have different isomerization performance; amygdalin monomer did not occur isomerization in acid environment
isomerization under the effect of ammonia
sodium hydroxide. Conclusion: With the rise of decocting temperature results in the peak area of D-amygdalin and L-amygdalin gradually increased. Amygdalin monomer is stable in the acidic environment
Discussion on Quality Control of Armeniacae Semen Amarum and Its Preparations
Simultaneous Determination of Ephedrine Hydrochloride, -pseudo-ephedrine and Amygdalin in Xuanfei Zhike Oral Liquid by RP-HPLC
Research of Bioavailability of Chinese Materia Medica Preparation
Optimization of Extraction Technology for Effective Ingredients from Majie Pingchuan Cataplasma by Orthogonal Test and Transdermal Characteristic Investigation
Optimization of Extraction Technology for Qingzao Jiufei Decoction by Comprehensive Scoring Method
Related Author
Ji-ping LI
Xia CHEN
LIU Zhi-hui
WANG Ning
LIU Rui
TONG Yan
DONG Mei-hong
YANG De-bin
Related Institution
Center for Drug Evaluation,National Medical Products Administration