Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer

ZHAO Ya-juan; LI Qing-shan; LIU Lan-fang; LV Xi-ying; ZHANG Li; DU Xin-sheng

doi:10.11653/syfj2013080323

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Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer

更新时间：2024-01-04

- Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 8, Pages: 323-325(2013)
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- DOI：10.11653/syfj2013080323
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- Published：2013
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ZHAO Ya-juan, LI Qing-shan, LIU Lan-fang, et al. Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 323-325.
DOI：

ZHAO Ya-juan, LI Qing-shan, LIU Lan-fang, et al. Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 323-325. DOI： 10.11653/syfj2013080323.

摘要

目的: 探讨艾迪注射液对肺癌放疗患者血清细胞因子的影响。方法: 将40例肺癌患者

随机分为治疗组(20例)和对照组(20例)

两组均予三维适行放疗(3DCRT)

治疗组在此基础上加用艾迪注射液。比较放疗前后两组患者血清中白细胞介素-6(IL-6)

肿瘤坏死因子-α(TNF-α)和转化生长因-β(TGF-β)水平的变化及放射性肺炎(RP)发生率的差异。结果: 治疗组在放疗结束后细胞因子IL-6

TNF-α和TGF-β的水平明显低于对照组

二者比较差异有显著性(P<0.05);两组RP的发生率相近。结论: 艾迪注射液能降低肺癌放疗患者血清细胞因子IL-6

TNF-α和TGF-β的水平

延缓放射性肺炎的进展

有效预防放射性肺炎的发生。

Abstract

Objective: It is to explore the effect of Aidi Injecttion on the expression of radiotherapy for lung cancer patients. Method: Fourty cases of lung cancer were randomly divided into treatment group (20 cases) and control group (20 cases).The two groups were given three-dimensional conformal radiation therapy (3D CRT).Meanwhile

the treatment group was added Aidi injecttio.There were some indices compared before and after radiotherapy including the serum interleukin-6(IL-6)

the tumor necrosis factor-α(TNF-α) and the transforming growth factor-β(TGF-β).And then

the incidence of the radiation pneumonia were also compared between two groups. Result: After the end of treatment

the IL-6

the TNF-α and the TGF-β of the treatment group were lower than those of the control group. There was significant difference(P<0.05). Nevertheless there were no significat differences between two groups about incidence of the radiation pneumonitis. Conclusion: Aidi injecttion could relieve the progress of Radiation pneumonitis through decreasing levels of the IL-6

the TNF-α and the TGF-β

thus

prevention of the occurrence of radiation pneumonia.

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Related Institution

Anshun City People’s Hospital

Henan Province Hospital of Traditional Chinese Medicine

The Second Clinical Medical College， Henan University of Chinese Medicine

The Affiliated Cancer Hospital of Zhengzhou University/Henan Cancer Hospital

Henan Province Hospital of Traditional Chinese Medicine/The Second Affiliated Hospital of Henan University of Chinese Medicine

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