LI Xiang-ping, LI Dian-ming, WANG Huan. Influence of Danhong Injection on Cerebrovascular Hemodynamic Parameters and Nerve Function Related Factors in Patients with Transient Ischemic Attack[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(9): 336-338.
DOI:
LI Xiang-ping, LI Dian-ming, WANG Huan. Influence of Danhong Injection on Cerebrovascular Hemodynamic Parameters and Nerve Function Related Factors in Patients with Transient Ischemic Attack[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(9): 336-338. DOI: 10.11653/syfj2013090336.
Influence of Danhong Injection on Cerebrovascular Hemodynamic Parameters and Nerve Function Related Factors in Patients with Transient Ischemic Attack
Objective: To study the influence of Danhong injection on cerebrovascular hemodynamic parameters and nerve function related factors in patients with transient ischemic attack. Method: Fifty-eight patients with transient ischemic attack in our hospital were selected and randomly divided into control group and observation group with 29 cases in each group
the control group were treated with routine treatment
the observation group were treated with Danhong injection 40 mL+5% glucose solution iv
daily
for 2 weeks
based on the treatment of control group. Then cerebrovascular hemodynamic parameters and serum neuron specific enolase(NSE)
S100B protein (S-100B)
myelin basic protein (MBP)
glial fibrillary acidic protein (GFAP) of two groups before and after the treatment after 1 and 2 weeks were compared. Result: The mean flow velocity(Vmean)
maximum-portal flow velocity(Vmax)
minimum flow velocity (Vmin) and mean blood flow(Qmean) of observation group after the treatment for 1 and 2 weeks were higher than those in control group
resistance (R) were lower than that of control group
serum NSE
S-100B
MBP and GFAP were all lower than those of control group (all P<0.05). Conclusion: The influence of Danhong injection on cerebrovascular hemodynamic parameters and nerve function related factors in patients with transient ischemic attack is significant
and the injection can effectively improve the blood supply in brain.
Influence of Danhong Injection on Cerebrovascular Hemodynamic Parameters and Nerve Function Related Factors in Patients with Transient Ischemic Attack
Efficacy-driving Mechanism of Danhong Injection for Stable Angina Pectoris Based on Composition-activity Relationship of Target Modules
Class-imbalance Prediction and High-dimensional Risk Factor Identification of Adverse Reactions of Traditional Chinese Medicine with Centralized Monitoring in Real-world Hospitals
Research Progress on Pharmacological Mechanism of Danhong Injection in Treatment of Cardiovascular and Cerebrovascular Diseases
Analysis of Modular Network Mechanism of Danhong Injection in Treatment of Coronary Angina Pectoris
Related Author
LI Xiang-ping
LI Dian-ming
WANG Huan
ZONG Wenjing
LIU Jun
YANG Wei
NIU Qikai
ZHANG Siqi
Related Institution
People’s Hospital of Jiyuan City
Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences
Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
School of Mathematics and Computational Science,Hunan University of Science and Technology