MA Yu, PAN Xiu-qing, REN Yue-qin, et al. Clinical Effect of Naomaitai Capsule on Vascular Dementia Patients[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(9): 339-341.
DOI:
MA Yu, PAN Xiu-qing, REN Yue-qin, et al. Clinical Effect of Naomaitai Capsule on Vascular Dementia Patients[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(9): 339-341. DOI: 10.11653/syfj2013090339.
Clinical Effect of Naomaitai Capsule on Vascular Dementia Patients
Objective: To study the effect of Naomaitai capsule on cognitive dysfunction of vascular dementia patients. Method: Eighty four vascular dementia patients were randomly divided into therapeutic group and control group (n=41 each). The therapeutic group was treated by Naomaitai capsule (2 capsules
tid) and the control group by Naofukang (2 tablets
tid). The therapeutic course was 12 weeks. Before and after treatment
mimi-mental state examination (MMSE) grade and variation of frenquently appeared potential (P300) were evaluated. Clinical efficacy was evaluated for the two groups. Result: After the therapeutic course
the total efficacy of the observation group was better than that of the control group
the difference was statistically significant (p<0.05). In two groups MMSE scores
P300 latency and P300 amplitude was significantly improved after treatment compared with those before treatment (P<0.05 or P<0.01). The improvement in the treatment group was better than that in the controls. Conclusion: Naomaitai capsule for treating vascular dementia shows good efficacy and less adverse reactions. The capsule can promote cognitive recovery.