Chemical Components and Bioactivity of Volatiles from Kernels of

XIE Xiu-chao; CHEN Wen-qiang; DENG Bai-wan; PENG Hao; ZHANG Xiao-wei; ZHANG Man

doi:10.11653/syfj2013100076

您当前的位置：

首页 >

文章列表页 >

Chemical Components and Bioactivity of Volatiles from Kernels of

更新时间：2024-01-04

- Chemical Components and Bioactivity of Volatiles from Kernels of
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 10, Pages: 76-80(2013)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/syfj2013100076
  CLC：
- Published：2013
- 稿件说明：
移动端阅览
XIE Xiu-chao, CHEN Wen-qiang, DENG Bai-wan, et al. Chemical Components and Bioactivity of Volatiles from Kernels of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(10): 76-80.
DOI：

XIE Xiu-chao, CHEN Wen-qiang, DENG Bai-wan, et al. Chemical Components and Bioactivity of Volatiles from Kernels of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(10): 76-80. DOI： 10.11653/syfj2013100076.

摘要

目的: 研究三尖杉种仁挥发油的化学成分及其生物活性。方法: 采用索氏回流法提取三尖杉种仁的挥发油

利用气相色谱-质谱联用技术(GC-MS)分离和鉴定其化学成分

并通过滤纸片扩散法和MTT法初步研究挥发油的抑菌及细胞毒活性。结果: 从三尖杉种仁的挥发油中共鉴定出23种化学成分

主要为油酸(34.53%)、棕榈酸(12.04%)、亚油酸丁酯(9.56%)、油酸乙酯(9.31%)等;活性检测表明挥发油样品对金黄色葡萄球菌Staphylococcus aureus、大肠埃希菌Escherichia coli和沙门氏菌Salmonella typhl显示较强的抑制作用

对慢性粒细胞白血病细胞株K562具有较高细胞毒活性

并呈剂量-效应依赖关系

IC50 16.14 mg·L-1。结论: 三尖杉种仁的挥发性成分主要为脂肪酸类、脂肪烷烃类及萜类

有抗菌、抗肿瘤活性

具有进一步开发利用的价值。

Abstract

Objective: To study the chemical components and bioactivity of volatiles from the kernels of Cephalotaxus fortunei. Method: the essential oils were extracted with Soxhlet extraction method. The chemical composition were separated and identified by gas chromatography-mass spectrometry(GC-MS). Study the antibacterial and antitumor activity of fatty acids by filter paper diffusion and MTT method. Result: Twenty-three components were identified from the kernel of C. fortunei

the main components were oleic acid (34.53%)

palmitic acid (12.04%)

linnleic acid

butyl ester (9.56%)

ethyl oleate (9.31%) and so on. The volatiles exhibited strong antimicrobial activities against Staphylococcus aureus

Escherichia coli and Salmonella. In addition

the sample had cytotoxic activity against K562 tumor cell lines. Conclusion: The volatiles were composed of aliphatic acids

alkanes and terpenoids

exhibited antimicrobial and cytotoxic bioactivities.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Reviews on Chemical Compositions and Pharmacological Effect of Gelsemium elegans

Earliest Investigation on Application of Isolated Heart Perfusion Technique to Evaluate Bioactivity of Antianginal Chinese Medicine

Volatile Oils in Root of Elaeagnus henryi by HS-SPME-GC-MS

Volatile Oils in Stem of by Head-pace Solid Micro-extraction

Isolation, Identification and Antimicrobial Activity of Endophytic Fungi from Medical Plant

Related Author

Shu-peng WU

Chun-li HU

Jing KANG

Meng ZHAO

Ya-ting ZHAO

HONG Li-ya

NI Wei -fang

ZHU She-min

Related Institution

Shanxi Normal University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰