Determination of Five Kinds of Effective Components in Guang Tong Xiao Water Extract by LC-MS/MS

ZHU Li; WUANG Rui; LI Peng-yue; DENG Zhi-hao; ZHAO Bao-ming

doi:10.11653/syfj2013100098

您当前的位置：

首页 >

文章列表页 >

Determination of Five Kinds of Effective Components in Guang Tong Xiao Water Extract by LC-MS/MS

更新时间：2024-01-04

- Determination of Five Kinds of Effective Components in Guang Tong Xiao Water Extract by LC-MS/MS
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 10, Pages: 98-102(2013)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/syfj2013100098
  CLC：
- Published：2013
- 稿件说明：
移动端阅览
ZHU Li, WUANG Rui, LI Peng-yue, et al. Determination of Five Kinds of Effective Components in Guang Tong Xiao Water Extract by LC-MS/MS[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(10): 98-102.
DOI：

ZHU Li, WUANG Rui, LI Peng-yue, et al. Determination of Five Kinds of Effective Components in Guang Tong Xiao Water Extract by LC-MS/MS[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(10): 98-102. DOI： 10.11653/syfj2013100098.

摘要

目的: 建立同时测定广痛消水提物中延胡索乙素、芍药苷、小檗碱、厚朴酚、和厚朴酚含量的方法。方法: 采用LC-MS/MS联用方法。结果: 芍药苷、延胡索乙素、小檗碱、厚朴酚、和厚朴酚线性范围分别为0.882 8～113(r=0.999 8)

1.543 8～49.4(r=0.999 5)

0.904 7～115.8(r=0.999 7)

0.881 3～112.8(r=0.999 4)

0.165 6～21.2 mg·L-1(r=0.999 9)。加样回收率分别为1.998%

1.14%

3.117%

1.828%

1.596%。结论: 该法专属性强、快速灵敏

可用于广痛消水提物中延胡索乙素、芍药苷、小檗碱、厚朴酚、和厚朴酚的含量测定。

Abstract

Objective: To develop a LC-MS/MS method for the determination of tetrahydropalmatine

paeoniflorin

berberine

magnolol and honokiol in Guang Tong Xiao water extract. Method: To measure the content of the target samples by LC-MS/MS method. Result: tetrahydropalmatine

paeoniflorin

berberine

magnolol and honokiol were all analyzed exactly

The linear ranges were 0.882 812 5-113(r=0.999 8)

1.543 75-49.4(r=0.999 5)

0.904 687 5-115.8(r=0.999 7)

0.881 25-112.8(r=0.999 4)

0.165 625-21.2 mg·L-1(r=0.999 9) respectively. The spike recovery were 1.998%

1.14%

3.117%

1.828% and 1.596%. Conclusion: A sensitive

accuracy and suitable LC-MS/MS method has been developed

and the method can be applied for the detemination of tetrahydropalmatine

paeoniflorin

berberine

magnolol and honokiol in Guang Tong Xiao aqueous extract.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Grade Evaluation of Magnoliae Officinalis Cortex Processed with Ginger Juice Based on Relative Quality Constant

HPLC Method for the Quantitative Determination of Magnolol and Honokiol in the Huoxiang Zhengqi Wan

Determination of magnolol and honokiol in XIANGSHA YANGWEI GRANULES by RP-HPLC

Determination of Hesperidin,Eugenol,Honokiol and Magnolol in Shenxiang Yangwei Capsule by HPLC

Principal,Assistant,Compleaent,Guide Compatibility of Banxiahoupo Decoction on Contents of Honokiol and Magnolol

Related Author

Quan ZHANG

Wen-guang JING

Zhe DENG

Jie DU

Qing-shan LAN

ZHAO Xian-hong1

LI Xiang-ri1

YUAN Yong-sheng2

Related Institution

China National Traditional Chinese Medicine Co. Ltd.

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College

Dali University,Dali

The First People’s Hospital of Lianyungang City Lianyungang

Jiangsu Kanion Pharmaceutical Co. Ltd

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰