Objective: To study the effect of Fuke Qianjin tablets on inflammatory cytokines in blood serum in rats. With chronic pelvic inflammatory disease. Method: The rat chronic pelvic inflammation model was established by mixed bacteria of Staphyloccocus aureus

Escherichia coli and M.urealyticum. The rats were randomly divided into 7 groups. Fuke Qianjin tablets in high

middle and low dosage were used to treat chronic pelvic inflammation model rat for 21 days. The content of blood serum interleukin-1β(IL-1β)

tumor necrosis factor-α(TNF-α)and interleukin-10(IL-10)in chronic pelvic inflammation model rat was measured by enzyme-linked immumsorbent assay(ELASA).Pathologic change of uterus was measured by a microscope. Result: Visual inspection: the Fuke Qianjin tablets in high

middle and low dosage uterine swelling

hyperemia significantly reduced

the structures were clear. Light microscopic inspection: The Fuke Qianjin tablets in high

middle and low dosage can suppression of inflammatory cells in the rat endometrial hyperplasia

to promote its lesion repair of epithelial cell proliferation alleviates seasonal congestion and edema.Serum expressions of IL-1β

TNF-α in model group were markedly higher than those in normal control group(P<0.01). Serum expressions of IL-10 in model group were markedly lower than those in normal control group(P<0.01).Compared with model group

the serum expressions of IL-1β

TNF-α were significantly lower in Fuke Qianjin tablets high and middle groups(P<0.01

P<0.05). Serum expressions of IL-10 were markedly higher in Fuke Qianjin tablets high and middle groups (P<0.01). The serum expressions of IL-1β and IL-10 in Fuke Qianjin tablets low group were higher and lower than those in model group(P<0.05). Conclusion: Fuke Qianjin tablets promote the recovery of morphology and physiological function of damaged tissues and cells. Its mechanism may be associated with reduced promoting inflammatory cytokines IL-1β

TNF-α release to promote the anti-inflammatory cytokine IL-10 expression

regulation of Th1/Th2 balance related.