Objective: To establish HPLC fingerprint of Yinqiao Jiedu soft capsules. Method: HPLC was used with Kromasil C18 column(4.6 mm×250 mm

5 μm)

mobile phase of acetonitrile-0.1%H3PO4 in a gradient elution

detection wavelength was 327 nm

flow rate was 1.0 mL·min-1

and column temperature was 30 ℃.Fingerprints of 10 batches of Yinqiao Jiedu soft capsules were established. Result: Under these selected spectrum condition

14 common peaks were marked in fingerprints of 10 batches of Yinqiao Jiedu soft capsules

similarity of 10 batches soft capsules were more than 0.97. Conclusion: This method had good precision

repeatability and stability

which were satisfied to comprehensive evaluation for quality of Yinqiao Jiedu soft capsules.