Objective: To explore the effects of Jiawei Buyang Huanwu decoction on diabetic cardiomyopathy(DCM) patients' plasma B-type natriuretic peptide (BNP)

C-reactive protein (CRP) and glycosylated hemoglobin (HbA1c) change levels. Method: The subjects were divided into diabetic control group (30 cases) and DCM group (23 cases). The DCM group

on the basis of conventional western medicine

plus Jiawei Buyang Huanwu decoction

after 3 weeks of treatment

and then measure the plasma BNP

CRP

and HbA1c level before and after treatment. Result: Diabetic cardiomyopathy patients' BNP

CRP and HbA1c significantly higher than that of the diabetic control group (P<0.05) and DCM group

after the treatment of Jiawei Buyang Huanwu decoction

BNP and CRP decreased (P<0.05) than before treatment

while the change of HbA1c level is not statistically significant before and after treatment. Conclusion: The higher levels of BNP and CRP can reflect the lesion severity of DCM as a clinical serological markers

while Jiawei Buyang Huanwu Decoction can reduce their levels

displaying its good effect on the treatment of DCM.