Objective: To investigate the efficacy of Ginkgo leaf dripping pill in auxiliary treatment of unstable angina pectoris (UAP) and the influence on P-selectin. Method: Ninety-four patients with unstable angina pectoris were randomly divided into observation group and control group (n=47 each). Patients in two groups were both given conventional treatment

including nitrates

anti-platelet drugs

beta blockers

calcium antagonists

and Ginkgo leaf dripping pill (5 tablets at a time

tid orally

for 12 weeks) was used in the observation group. Nitroglycerin tablets of 0.5 mg were used for temporarily sublingual when angina pectoris attacks happened. Frequency of angina pectoris and dosage of nitroglycerin

heart blood stasis syndrome score and serum P-selectin levels were record every week. Result: Total effective rate of the observation group (95.74%) was better than the control group (82.99%) (P<0.05). Heart blood stasis syndrome score of the observation group was lower than that in the control group (P<0.01). The effective rate of Chinese medicine syndrome in the observation group (95.74%) was better than that (80.85%) in the control group ( P<0.05). Frequency of angina pectoris attacks and nitroglycerin consumption of the observation group were significantly lower than those in the control group (P<0.01). Levels of serum P-selectin in the observation group was lower than that in the control group (P<0.01). Conclusion: Ginkgo leaf dripping pill could reduce the frequency of angina pectoris attacks

improve symptoms and clinical curative effect. It can also reduce the level of P-selectin

inhibit the platelet aggregation and inflammation.