LI Chong, WANG Yan-fang, DING Chang-xia. Clinical Observation of Shenqi Baiji Soup on the Treatment of Stress Ulcer after Acute Cerebral Stroke[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(12): 297-299.
DOI:
LI Chong, WANG Yan-fang, DING Chang-xia. Clinical Observation of Shenqi Baiji Soup on the Treatment of Stress Ulcer after Acute Cerebral Stroke[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(12): 297-299. DOI: 10.11653/syfj2013120297.
Clinical Observation of Shenqi Baiji Soup on the Treatment of Stress Ulcer after Acute Cerebral Stroke
Objective: To evaluate the clinical effect of Shenqi Baiji soup (SBS) on the treatment of stress ulcer (SU) after acute cerebral stroke. Method: One hundred and four SU patients were randomly dividing into observation group and control group (n=52 each). The control group was injected intravenously with omeprazole 20 mg two times a day:cimetidine 200 mg intravenous dripping
6 h a day. Observation group was additionally given SBS
one dose daily through stomach tube.Two groups were treated with medicine until the occult blood in excrement showed negative result. Gastric juice occult blood and pH value were monitored. Hemoglobin
the count of red blood cell
hematocrit and excrement occult blood were determined. Plasma endothelin level (ET-1)
gastrin level
incidence of abdominal distention
diarrhea and gastric retention were also tested and investigated. Result: The clinical effect of observation group was obviously better than that of the control group(P<0.05)after treatment. Gastric juice pH value of observation group was higher than that of control group. Blood ET-1 and gastrin level were lower than those of control group(P<0.01). The incidence of abdominal distention
diarrhea
gastric retention and hemorrhoea in observation group was lower than those of control group(P<0.01); fecal occult blood clearance time (8.2±2.64) d in observation group was shorter than that (10.5±2.92) d of the control group (P<0.05). Conclusion: SBS can lower SU patients' ET-1 and gastrin level
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