Effect of Maintenance Treatment by Traditional Chinese Medicine Syndrome Differentiation on Life Quality and Progress-free Survival of Patients with Advanced Non-small Cell Lung Cancer after Chemotherapy
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Effect of Maintenance Treatment by Traditional Chinese Medicine Syndrome Differentiation on Life Quality and Progress-free Survival of Patients with Advanced Non-small Cell Lung Cancer after Chemotherapy
Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 13, Pages: 319-322(2013)
WANGH Lu, SUN Zhi-xia, FENG Guang-qiang, et al. Effect of Maintenance Treatment by Traditional Chinese Medicine Syndrome Differentiation on Life Quality and Progress-free Survival of Patients with Advanced Non-small Cell Lung Cancer after Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(13): 319-322.
DOI:
WANGH Lu, SUN Zhi-xia, FENG Guang-qiang, et al. Effect of Maintenance Treatment by Traditional Chinese Medicine Syndrome Differentiation on Life Quality and Progress-free Survival of Patients with Advanced Non-small Cell Lung Cancer after Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(13): 319-322. DOI: 10.11653/syfj2013130319.
Effect of Maintenance Treatment by Traditional Chinese Medicine Syndrome Differentiation on Life Quality and Progress-free Survival of Patients with Advanced Non-small Cell Lung Cancer after Chemotherapy
Objective:To investigate the effect of maintenance treatment by traditional Chinese medicine (TCM) syndrome differentiation on life quality and progress-free survival (PFS) of patients with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy. Method: Seventy-six patients with NSCLC were randomly divided into observation group and control group (n=39 each). The two groups were treated with first-line chemotherapy for 4 to 6 weeks. The control group was regularly followed-up. The observation group was received TCM syndrome differentiation treatment. Follow-up data about PFS was analyzed
besides
life quality and clinic symptom of patients before and 12 weeks after treatment were evaluated. Result: After treatment
physical function
role function
emotional function and total life quality in observation group were higher than those in control group (P<0.05). Fatigue
dyspnoea
insomnia and appetite loss scores in observation group were lower than those in control group (P<0.05). PFS of observation group was (7.2±1.32) months
which was longer than (4.4±0.57) months of control group (P<0.01). Scores of cough
phlegm
blood in phlegm
shortness of breath
chest pain
lassitude
anorexia
insomnia and others in observation group were lower than those in control group (P<0.01). Conclusion: Maintenance treatment by TCM syndrome differentiation on patients with advanced NSCLC can improve life quality and clinic symptom