Objective:To investigate the clinical efficacy of combination of Chinese traditional and western medicine on ectopic pregnancy. Method: Ninety-six subjects were randomly divided into observation group and control group (n=48 each). Control group was given methotrexate (MTX) 50 mg·m-2 by intramuscular injection

once. Observation group was received Shaofu Zhuyu decoction on the basis of control group

and the prescription was adjusted according to the level of human chorionic gonadotrophin (β-HCG)

1 dose daily. The decoction was prepared daily and taken 2 times (half by half)

for 4 weeks. Vital signs and serum β-HCG level were monitored

the extrauterine pregnancy package of block was monitored by B ultrasonic

and tubal patency tests were applied. Result: The success rate of observation group (91.66%) was superior to that in control group (72.92%) (P<0.05). The recovery duration of β-HCG

the duration of abdominal pain disappearance and the duration for absorption of uterine rectal pouch effusion in the observation group were less than those in the control group (P<0.05). The enclosed mass in the observation group after treatment was less than that in control group (P<0.01). Tubal patency rate of observation group (89.65%) was superior to that in control group (70.37%) (P<0.05). Conclusion: The conservative treatment of combination of Chinese traditional and western medicine for ectopic pregnancy could kill fetus

promote quick absorption of enclosed mass

maintain tubal patency

preserve the fertility. It is safe and worthy for being widely used in clinical treatment.