LI Xiao-ning, YANG Yin-hua, ZHAO Bo-chen, et al. Optimization of Supercritical CO Fluid Extraction Process for Volatile Oil from [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(14): 27-29.
DOI:
LI Xiao-ning, YANG Yin-hua, ZHAO Bo-chen, et al. Optimization of Supercritical CO Fluid Extraction Process for Volatile Oil from [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(14): 27-29. DOI: 10.11653/syfj2013140027.
Optimization of Supercritical CO Fluid Extraction Process for Volatile Oil from
Objective: To optimize supercritical CO2 fluid extraction process parameters of volatile oil from Angelica sinensis. Method: With composite score of the content of ligustilide and yield of volatile oil as index
the content of ligustilide was determined by HPLC
L9(34) orthogonal test was used to investigate effect of extraction temperature
extraction pressure
extraction time on extraction efficiency. Result: Optimum process parameters were as follows:extraction pressure 30 MPa
extraction temperature 50℃
extraction time 2 h
flow rate of CO2 25 L·h-1
pressure of separation kettle I 8 MPa with temperature at 50℃
separation pot II pressure of the system tail pressure with temperature at 35℃. Conclusion: This optimized process was stable and feasible
which could be adopted to extract volatile oil from A. sinensis with high yield and good quality.