LI Min-lan, CHEN Zhi-qin, ZHANG Zhen-ling. Comparision on the Effect of Different Production of Rehmanniae Radix in Siwu Prescription on T Lymphocyte Subsets in Mice[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(14): 215-218.
DOI:
LI Min-lan, CHEN Zhi-qin, ZHANG Zhen-ling. Comparision on the Effect of Different Production of Rehmanniae Radix in Siwu Prescription on T Lymphocyte Subsets in Mice[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(14): 215-218. DOI: 10.11653/syfj2013140215.
Comparision on the Effect of Different Production of Rehmanniae Radix in Siwu Prescription on T Lymphocyte Subsets in Mice
Objective: To compare the effects of different processed products of Rehmanniae Radix in Siwu prescription
and the difference between raw rehmannia and prepared rehmannia. Method: Kunming female mice were injected
on day 1
2
3 respectively celiac injection (ip) cyclophosphamide (CTX) 80 mg·kg-1 to establish immunosuppression model. After 7 days of administration
the spleen and thymus
acquisition lymphocyte sample were collected. Flow cytometry instrument was used to test CD3+
CD4+
CD8+. Result: The prepared Rehmannia Radix of Siwu prescription could improve the immune suppression of spleen and thymus index (P<0.05)
and at the same time
improve CD3+
CD4+
CD8+lymphocytes (P<0.01) and CD4+/CD8+ Conclusion: The prepared Rehmannia Radix of Siwu prescription can improve the T cell subsets. Rehmanniae Radix with different processed methods has an influence on the immune function.