Objective: To observation the clinical efficacy Jiawei Dachaihu Tang in the treatment of phlegm-stasis blocking type obstructive sleep apnea-hypopnea syndrome(OSAHS). Method: Seventy-eight patients with phlegm-stasis blocking type obstructive sleep apnea-hypopnea syndrome were randomly divided into treated group (n=52) and control group (n=26). Patients in the control groups were treated with basic treatment

complications therapy

drug therapy

airway pressure therapy and other comprehensive treatment. Jiawei Dachaihu tang was used in the treated group and 15 days as one cycle. Using polysomnography (PSG) monitoring the sleep apnea-hypopnea index (AHI)

mean nocturnal SaO2

minimum SaO2 of the night

using the Epworth Sleepiness Scale (ESS) Evaluation of excessive daytime sleepiness

using the SF-36 scale evaluation of patients living quality. Result: The total efficacy of the treated group (96.15%) was significantly better than the control group (80.77%) (P<0.05). After treatment

AHI

ESS score and SaO2<90% ratio of treated group were less than the control group(P<0.05

P<0.01). Nighttime minimum SaO2 level of treated groups were with higher than control group(P<0.01). Physiological function

social function

physical function

mental health

role emotional

vitality

general health scores of patients in treated group were higher than patients in control group (P<0.01). Conclusion: The Jiawei Dachaihu tang in treating of OSAHS have significant clinical effect

it can improve the clinical symptoms and clinical signs

improve patient quality of life

improve clinical outcomes

worthy of clinical use and is worth for clinical use.