Objective: To explore the relationships between prescription and syndrome on Chinese herbal medicines with properties of cold or hot. Method: Data of Sophorae Flavescentis Radix

Gentianae Radix et Rhizoma

Isatidis folium

Cinnamoni Cortex

Eudiae Fructus

Piperis Fructus were downloaded from CBM database. The rules of disease

pattern/syndrome

symptom

and decoction were mined out with data slicing algorithm. The results are visually demonstrated with cytoscape. Result: For diseases

there was no clear separation between cold herbs and hot herbs

because they covered disease of several system. For traditional Chinese Medicine(TCM) pattern/syndrome

the hot herbs were mainly focused on yang deficiency

coagulated cold

qi stagnation

blood stasis. For cold herbs

they were mainly focused on dampness-heat

yin deficiency

heat-toxicity

wind-heat. For symptoms

hot herbswere mainly focused on diseases of digestive and nervous systems. But for cold herbs

not only the digestive system

but also the skin diseases

i.e.

pruritus and papule were included. For decoctions

formulae of Wen-Yang and Wen-Li were associated with hot herbs

on the country

cold herbs were mainly focused on formulae of Qing-Re and He-Jie. Take digestive disease for example

these relationships between prescription and syndrome are existed. Conclusion: Text mining

together with artificial reading for anti-noising

is an important approach in exploring the rules among disease

TCM pattern/syndrome

symptom

and prescription associated with cold and hot herbs.