Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis

ZHANG Zhen-wei; ZHANG Na-na; SHI Lei

doi:10.11653/syfj2013160018

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Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis

更新时间：2024-01-04

- Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 16, Pages: 18-21(2013)
- 作者机构：
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- 基金信息：
- DOI：10.11653/syfj2013160018
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- Published：2013
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ZHANG Zhen-wei, ZHANG Na-na, SHI Lei. Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(16): 18-21.
DOI：

ZHANG Zhen-wei, ZHANG Na-na, SHI Lei. Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(16): 18-21. DOI： 10.11653/syfj2013160018.

摘要

目的: 建立清热解毒口服液生产工艺的综合评价模式

并应用于该制剂的生产监控。方法: 选择清热解毒口服液为研究对象

以共有峰为多变量

采用主成分分析、因子分析等方法实现对数据的压缩、解释

通过少量主分量分析揭示制剂整体质量的变化。结果: 最佳提取工艺为加10倍量水提取2次

每次100 min。结论: 降维分析法能简化分析过程

且能深刻揭示原始数据的内在规律

适用于对中药整体质量的控制。

Abstract

Objective: To Establish comprehensive evaluation model of production process of Qingre Jiedu oral liquid

and apply to production monitoring of this preparation. Method: Qingre Jiedu oral liquid was selected as study object

with shared peaks as multivariate variables

principal component analysis

factor analysis and other methods were adopted to achieve data compression and interpretation

and the overall quality changes of preparations was revealed by a small amount of principle component analysis. Result: Optimum extraction technology of Qingre Jiedu oral liquid was:extracted 2 times with 10 times the amount of water

100 min per time. Conclusion: Dimensionality reduction analysis could simplify analysis process and reveal inherent laws of raw data penetratingly

it was suitable for control of the overall quality of traditional Chinese medicine.

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Related Institution

Jiangyin Tianjiang Pharmaceutical Co. Ltd.，Jiangyin

Shandong Technical Innovation Center for Traditional Chinese Medicine Treatment of Respiratory Diseases，Shandong Hongjitang Pharmaceutical Group Co. Ltd.

Shandong Institute for Food and Drug Control

School of Pharmacy，State Key Laboratory of Southwestern Chinese Medicine Resources， Chengdu University of Traditional Chinese Medicine

Hunan Polytechnic of Environment and Biology

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