Objective: To investigate the clinical efficacy of ruiyun procedure for hemorrhoids(RPH) Combined with hemorrhoidlysant injection in treating hemorrhoids. Method: One hundred sixty patients with hemorrhoids were divided into two groups according to control trail design by randomized method.Eighty patients in control group were treated with RPH and another has eighty patients in testing group were treated with RPH combined with hemorrhoidlysant injection.The changes of the symptom and physical sign at pre-therapy and post-treatment were compared

and the complications after operation were observed

the cure rate at three and six months after operation and the recurrence rate at 1 and 2 years after operation were observed. Result: The scores of symptom and physical sign were obviously decreased in both groups which after treatment (P<0.05); there was no difference in the scores for each symptom and physical sign between two groups at three months after operation; there was significant difference between the two groups in hemorrhage score

decreasing at six months after treatment (P<0.05) and there was no difference in other indexes. The effects of the treatment between the two groups at three months and six months after operation showing no significant difference

but there is significant difference in recutrence rate at the two years after operation. No serious adverse reactions occurred. Conclusion: RPH combined with hemorrhoidlysant injection are effective and safe in treating hemorrhoids.