Objective: To investigate the clinical efficacy of Tingli Dazao Xiefei decoction and Daotan soup on the Tanyu Zufei type lung cancer. Method: The one hundred cases of Tanyu Zufei type lung cancer in middle and late period were randomly divided into control group and treatment group

50 case. each group. The control group only used western medicine according to chemotherapy scheme

and the treatment groups were treated with lung cancer prescription based on the treatment of control group. After 3 months

the short term curative effect

the improvement of life quality

the changes of body weight

the improvement of peripheral blood and immune function

and the occurrence of adverse reaction and the survival rates of patients after 1

3 and 5 years' treatment were observed. Result: The total effectiveness in control group and treatment group was 80.0% and 50.0%

respectively

the short term curative effect in treatment group was better than the control group

and there was significant difference(P<0.05);the improvement rate of life quality was 70.0% and 40.0%

respectively

the treatment group was better than the control group

and there was significant difference(P<0.05);the improvement rate of body weight was 16.0% and 20.0%

respectively

and there was no significant difference; the peripheral blood abnormality rates of treatment group was obviously lower than the control group

and there was significant difference(P<0.05);the treatment and control group were compared before and after treatment

the immune indexes (CD4+

CD8+

CD4+/CD8+and the activity of NK cell) all presented significant difference of different degree(P<0.05 and P<0.01)

and the immunity of treatment group was obviously improved; compared with control group

the occurrence rate of adverse reaction in treatment group was obviously lower than control group

and there was significant difference(P<0.05). The survival rates of patients after 1

3 and 5 years' treatment was better than the control group

and there was significant difference(P<0.05). Conclusion: The tanyuzufei type lung cancer was cured bylung cancer prescription combined with chemotherapy

and it could effectively relieve the clinical symptoms

improve the immunity

reduce the occurrence of adverse reaction

and improve the life quality

and the traditional Chinese medicine combined with chemotherapy has the efficacy and low toxicity.