Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis

JING Jing; GAO Zhen; LIAO Chun-yan; LI Feng-sen

doi:10.11653/syfj2013160343

您当前的位置：

首页 >

文章列表页 >

Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis

更新时间：2024-01-04

- Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 16, Pages: 343-348(2013)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/syfj2013160343
  CLC：
- Published：2013
- 稿件说明：
移动端阅览
JING Jing, GAO Zhen, LIAO Chun-yan, et al. Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(16): 343-348.
DOI：

JING Jing, GAO Zhen, LIAO Chun-yan, et al. Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(16): 343-348. DOI： 10.11653/syfj2013160343.

摘要

目的: 系统评价止嗽散治疗感染后咳嗽的疗效

为临床止嗽散治疗感染后咳嗽提供参考。方法: 按Cochrane系统评价方法

计算机检索CNKI

VIP

CBM 等数据库

检索时间从建库截止2011年10月

并手工检索相关文献

查找用止嗽散治疗或辅助治疗感染后咳嗽的随机对照试验。由2位研究者按照纳入排除标准筛选文献、评价质量并提取资料后

采用RevMan 5.0 软件进行Meta 分析。结果: 共纳入24个发表的RCT研究(n=2 147)

其中试验组1 087例

对照组1 060例;单纯止嗽散加减与西药治疗组治愈率固定效应模型显示合并OR=3.71

95%CI[2.96

4.66]

P<0.000 01;止嗽散及其加减方联合西药与西药治疗相比

固定效应模型显示合并OR=2.76

95%CI[1.98

3.85]

P<0.000 01。单纯止嗽散及其加减与西药治疗总有效率相比

固定效应模型显示合并OR=7.90

95%CI[5.67

11.01]

P<0.000 01;止嗽散及其加减方联合西药与西药治疗总有效率相比

固定效应模型显示合并OR=3.62

95%CI[2.22

5.92]

P<0.000 01。结论: 现有证据证明止嗽散及其加减治疗感染后咳嗽疗效较优

但由于研究试验方法学存在缺陷

且存在发表偏倚

研究结果尚不能充分肯定

仍需要高质量的研究试验进一步证实。

Abstract

Objective: A systematic review on treatment of infections by Zhisou san was carried out.Method: Meta-analysis of randomized controlled trial (RCT) was used

and RevMan 5.1 software for statistical analysis was adopted.Result: A total of 24 published RCT (n=2 147) was included

which was divided into the experimental group of 1 087 cases and the control group of 1 060 cases. In simple Zhisou san and western medicine groups the combined OR of cure rate of the group fixed effects model was 3.71

95% CI[2.96

4.66]

P<0.000 01; In Zhisou san combined with western medicine and western medicine

OR was 2.76

95% CI[1.98

3.85

P<0.000 01.The combined OR of Zhisou san was 7.90

95% CI[5.67

11.01]

P<0.000 01; OR of Zhisou san combined with Western medicine. Western medicine was 3.62

95% CI[2.22

5.92]

P<0.000 01.Conclusion: Zhisou san in treating infections may be effective

but the further confirmation by high-quality research trials was needed.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰