Optimization of Clarification Process of Shenyu Oral Liquid

SUN Li-xia; CHANG Gui-juan; LI Qiu-meng; ZHANG Nan-nan; BAI Xue-yuan; ZHAO Da-qing

doi:10.11653/syfj2013170004

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Optimization of Clarification Process of Shenyu Oral Liquid

更新时间：2024-01-04

- Optimization of Clarification Process of Shenyu Oral Liquid
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 17, Pages: 4-7(2013)
- 作者机构：
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- DOI：10.11653/syfj2013170004
  CLC：
- Published：2013
- 稿件说明：
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SUN Li-xia, CHANG Gui-juan, LI Qiu-meng, et al. Optimization of Clarification Process of Shenyu Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(17): 4-7.
DOI：

SUN Li-xia, CHANG Gui-juan, LI Qiu-meng, et al. Optimization of Clarification Process of Shenyu Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(17): 4-7. DOI： 10.11653/syfj2013170004.

摘要

目的: 优选参玉口服液的澄清工艺。方法: 以人参皂苷含量、总多糖含量、澄明度和稳定性为评价指标

考察KBT-ZTC絮凝澄清法、酶解法、微滤法、酶解-微滤法及絮凝澄清-微滤法对参玉口服液质量的影响。结果: 最佳澄清处理方法为絮凝澄清-微滤法

参玉口服液澄清稳定、有效成分保留率得以提高

人参皂苷Re、人参皂苷Rg1、人参皂苷Rb1、总多糖质量分数分别为0.331 1

0.282 8

0.098 4

96.33 mg·g-1。结论: KBT-ZTC絮凝澄清法与微滤法联用能有效除去杂质

保留有效成分

且工艺稳定

可作为参玉口服液的澄清工艺。

Abstract

Objective: To optimize clarification technology of Shenyu oral liquid. Method: Effects of KBT-ZTC flocculation

enzymatic

microfiltration

enzymatic-microfiltration and flocculation-microfiltration on quality of Shenyu oral liquid were investigated with the contents of ginsenoside and total polysaccharides

clarity and stability as evaluation indexes. Result: Optimum clarification method was flocculation-microfiltration which could improve retention rate of effective ingredients of Shenyu oral liquid and make this oral liquid clear and stable.The contents of ginsenoside Re

Rg1

Rb1 were 0.331 1

0.282 8

0.098 4 mg·g-1 and the content of total polysaccharides was 96.33 mg·g-1. Conclusion: Impurities could removed effectively and effective ingredients were retained by KBT-ZTC flocculation-microfiltration method

this process was stable and could be used as clarification technology of Shenyu oral liquid.

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