Objective: To observe the effect of the ethanol extracts of glossy privet leaf on hyperlipemia model of quail. Method: Hyperlipemia model of quail were induced by exogenous cholesterol and high fat diets until the liver's fatty degeneration

Quails were randomly divided into the normal group

the model group of high fatty

the zhibituo group (3 g·kg-1)

the high

middle and low dose group of ethanol extracts from glossy privet leaf (1.5

3

6 g·kg-1)

each group was administrated for according drug for 4 weeks. The serum content of triglyceride(TG) cholesterol(CHO)

low density lipoprotein cholesterol(LDL-C) and high density lipoprotein cholesterol(HDL-C) of each group was determined after administration. Meanwhile

the histopathologic examination in livers fatty degeneration was also detected. Result: The low dose of the extracts of glossy privet leaf could decreased the level of TG in sevum (P<0.05)

while the middle and high dose could significantly decreased the levels of CHO and TG in serum (P<0.01). High dose of extraction glossy privet leaf could significantly rise the level of HDL-C in serum while has counter effect on LDL-C. The coefficient of liver weight and the amount of hepatic fatty degeneration had been obviously reduced in both ethanol extract group (P<0.01). Conclusion: The ethanol extracts of glossy privet leaf have effects on preventing and treating the experimental hyperlipemia and liver's fatty degeneration of quail.