Chemical Constituents from Lateral Roots of

LI Xiao-hong; HE Cheng-jun; ZHOU Qin-mei; LIU Juan; GUO Li; PENG Cheng

doi:10.11653/syfj2013190086

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Chemical Constituents from Lateral Roots of

更新时间：2024-01-04

- Chemical Constituents from Lateral Roots of
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 19, Pages: 86-89(2013)
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- DOI：10.11653/syfj2013190086
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- Published：2013
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LI Xiao-hong, HE Cheng-jun, ZHOU Qin-mei, et al. Chemical Constituents from Lateral Roots of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(19): 86-89.
DOI：

LI Xiao-hong, HE Cheng-jun, ZHOU Qin-mei, et al. Chemical Constituents from Lateral Roots of [J]. Chinese journal of experimental traditional medical formulae, 2013, 19(19): 86-89. DOI： 10.11653/syfj2013190086.

摘要

目的: 研究附子Aconitum carmichaelii Debx. 的子根的化学成分。方法: 采用硅胶、MCI 以及 Sephadex LH-20 柱色谱等分离

运用波谱数据鉴定化合物的结构。结果: 从附子中分离得到12个化合物

分别鉴定为烟酰胺(1)、尿嘧啶(2)、次黄嘌呤(3)、腺苷(4)、尿苷(5)、5-羟甲基-吡咯-2-甲醛(6)、马齿苋酰胺E(7)、顺-对香豆酸-4-O-β-D-葡萄糖苷(8)、顺-阿魏酸-4-β-葡萄糖苷(9)、反-阿魏酸-4-β-葡萄糖苷(10)、异麦芽酚-葡萄糖苷(11)、2

6-三苯基-1-己烯(12)。结论: 除化合物 2 以外

其他化合物均为首次从该属植物中分离得到。

Abstract

Objective: To investigate the chemical constituents from the lateral roots of Aconitum carmichaelii. Method: A combination of various chromatographic techniques including column chromatography over silica gel

MCI

and Sephadex LH-20 were used to isolate the chemical constituents and their structures were elucidated by spectroscopic data analysis. Result: Twelve compounds were isolated and identified as nicotinamide (1)

uracil (2)

hypoxanthine (3)

adenosine (4)

uridine (5)

5-hydroxymethyl-pyrrole-2-carbaldehyde (6)

oleracein E (7)

cis-p-coumaric acid 4-O-β-D-glucoside (8)

cis-feruloyl-4-β-glucoside (9)

trans-feruloyl-4-β-glucoside (10)

isomaltol-glucoside (11) and 2

6-triphenylhex-1-ene (12). Conclusion: All the compounds were obtained from the genus Aconitum for the first time except compound 2.

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