HU Chao-qi, CHEN Xin, XU Hui-dan. Optimization of Stomach Bionic Transformation Technology for Schisandrae Chinensis Fructus by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 33-36.
DOI:
HU Chao-qi, CHEN Xin, XU Hui-dan. Optimization of Stomach Bionic Transformation Technology for Schisandrae Chinensis Fructus by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 33-36. DOI: 10.11653/syfj2013210033.
Optimization of Stomach Bionic Transformation Technology for Schisandrae Chinensis Fructus by Orthogonal Test
Objective: To optimize in vitro stomach bionic transformation process of Schisandrae Chinensis Fructus. Method: With the cream rate and the content of schisandrin as indexes
orthogonal test and single factor tests were adopted to investigate effects of the concentration of Schisandrae Chinensis Fructus decoction
volume ratio of decoction and artificial gastric juice
transformation time
transformation times
speed and temperature on in vitro stomach bionic transformation process.The content of schisandrin was determined by HPLC. Result: Optimun process was as following:decoction concentration 1.0 g·mL-1
volume ratio of decoction and artificial gastric juice (1:1)
temperature 37 ℃
speed 75 r·min-1
transformation time 1 h
conversion of 1 times. Conclusion: Optimized in vitro stomach bionic transformation process was stable and reliable
which established experimental basis for human metabolism transformation of Schisandrae Chinensis Fructus.