WEI Yi, TANG Han-qing, LI Xiao-hua, et al. Effects of Fuzi Lizhong Decoction on Immune Cell Factors in Rats with Spleen Yang Deficiency Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 179-182.
DOI:
WEI Yi, TANG Han-qing, LI Xiao-hua, et al. Effects of Fuzi Lizhong Decoction on Immune Cell Factors in Rats with Spleen Yang Deficiency Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 179-182. DOI: 10.11653/syfj2013210179.
Effects of Fuzi Lizhong Decoction on Immune Cell Factors in Rats with Spleen Yang Deficiency Syndrome
Objective: To explore the effects and mechanism of Fuzi Lizhong decoction(FZLZ) on immune cell factors in rats with spleen Yang deficiency syndrome. Method: One hundred Wistar rats were randomly divided into model group
FZLZ low-dosage group
middle-dosage group
high-dosage group of FZLZ and control group. Each group included 20 rats. Low-dosage group
middle-dosage group and high-dosage group were ig given with FZLZ according to 5
10
20 g·kg-1based on model group
once a day for four weeks. Then thymus index
spleen index
the contents of interleukin(IL) -2
IL-6
IL-10 and tumor necrosis factor-α(TNF-α) were examined. Result: Compared with control group
thymus index
spleen index
the contents of IL-2
IL-6 and TNF-α in model group reduced (P<0.05 or P<0.01)
however
the content of IL-10 increased significantly (P<0.01). Compared with model group
thymus index
spleen index
the contents of IL-2
IL-6 and TNF-α in both middle-dosage group and high-dosage group increased (P<0.05 or P<0.01)while the content of IL-10 reduced (P<0.05 or P<0.01). Conclusion: Fuzi Lizhong decoction can improve immune function of rats with spleen Yang deficiency syndrome by regulating the contents of IL-2
Influence of Energy Charge and Expression of CNTF mRNA in Rats with Spleen Yang Deficiency Syndrome after Administrated Fuzi Lizhong Decoction
Effect of Fuzi Lizhong Decoction on AQP4 in Rats with Spleen Yang Deficiency Syndrome and its Antidiarrheal Mechanism
Establishment of Rat Spleen Yang Deficiency Syndrome Insomnia Model and Effect of Fuzi Lizhong Decoction on it
Establishment of the Animal Model of Coronary Heart Disease due to Heart and Spleen Yang Deficiency Syndrome and Effects of Fuzi Lizhong Decoction Interference
Related Author
TANG Han-qing
TANG Han-qing
WEI Yi
LAO Chuan-jun
LI Ke-ming
CHEN Hua
TANG Han-qing
NIU Chaofeng
Related Institution
Youjiang Medical University for Nationalities
Dongzhimen Hospital, Beijing University of Chinese Medicine
The First School of Clinical Medicine, Shaanxi University of Chinese Medicine
Affiliated Hospital of Shaanxi University of Chinese Medicine
Second Clinical School of Medicine, Henan University of Chinese Medicine