Objective: To optimize extraction process of hypoglycemic effective parts from Anemarrhenae Rhizoma and identify its ingredients. Method: With yield of total saponins and extract yield as indexes

uniform design test was adopted to investigate effects of ethanol concentration

ethanol amount and extraction on technology;With yield of total saponins and xanthones as indexes

extraction times was screened by single factor test.The content of xanthones was determined by UV

while total saponins was determined by HPLC

main components of hypoglycemic effective parts from Anemarrhenae Rhizoma were identified by UPLC/Q-TOF-MS. Result: Optimal extracting technology was as following:extracted twice with eight times the amount of 80% ethanol for 1 h per time;Main components of hypoglycemic effective parts from Anemarrhenae Rhizoma included 43 timosaponins and 7 xanthones. Conclusion: This optimized technology was stable and feasibel

it provided a reference for drug developing of effective parts from Chinese materia medica

which were adopted to treat diabetes and its complications.