YUAN Yuan, BAO Jia-ke. Optimization of Percolation Process for Dregs in Compound Toothache Tinctures[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 21-23.
DOI:
YUAN Yuan, BAO Jia-ke. Optimization of Percolation Process for Dregs in Compound Toothache Tinctures[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 21-23. DOI: 10.11653/syfj2013230021.
Optimization of Percolation Process for Dregs in Compound Toothache Tinctures
Objective: To optimize percolation process of Valeriana officinalis dregs in compound V. officinalis toothache tinctures with pharmacodynamic indicators. Method: Changes of capillary permeability of mouse ear inflammation model was adopted
pharmacodynamic indicators of percolation process end-product of V. officinalis dregs were compared
effects of ethanol concentration
soaking time
ethanol amount and flow rate on percolation process were investigated by orthogonal test. Result: Pharmacodynamic effects of each factors on percolation process of V. officinalis dregs was in order of ethanol concentration>soaking time>ethanol amount>flow rate
optimum percolation process was as following:soaked 1 h with 15 times the amount of 75% ethanol at 3.0 BV· h-1. Conclusion: Optimized percolation process parameters were stable and reliable through pharmacodynamic tests
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