Optimization of Clarification Process of Dantao Granules

WU Jian-jun; LIU Xin; CHEN Li

doi:10.11653/syfj2013230036

您当前的位置：

首页 >

文章列表页 >

Optimization of Clarification Process of Dantao Granules

更新时间：2024-01-04

- Optimization of Clarification Process of Dantao Granules
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 23, Pages: 36-39(2013)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/syfj2013230036
  CLC：
- Published：2013
- 稿件说明：
移动端阅览
WU Jian-jun, LIU Xin, CHEN Li. Optimization of Clarification Process of Dantao Granules[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 36-39.
DOI：

WU Jian-jun, LIU Xin, CHEN Li. Optimization of Clarification Process of Dantao Granules[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 36-39. DOI： 10.11653/syfj2013230036.

摘要

目的: 优选丹桃颗粒的壳聚糖絮凝剂澄清工艺，并与乙醇沉淀法、离心法进行比较。方法: 以水浸出物收率、苦杏仁苷及芍药苷保留率为综合评价指标，选择壳聚糖加入量、絮凝时药液温度、药液pH为考察因素，通过正交试验优选丹桃颗粒的壳聚糖絮凝剂澄清工艺，并与乙醇沉淀法和离心法进行比较，确定最佳除杂工艺。结果: 优选的壳聚糖絮凝剂澄清工艺为加入10%药液量的1%壳聚糖澄清剂，药液pH 6.0，50℃保温;苦杏仁苷、芍药苷保留率均>89%，水浸出固形物量约下降19%，整体优于乙醇沉淀法和离心法。结论: 壳聚糖絮凝剂澄清法可作为丹桃颗粒提取液的除杂工艺，该工艺合理可行、稳定可靠，符合工业化生产要求。

Abstract

Objective: To optimize chitosan flocculant clarification process of Dantao granules and compare with ethanol precipitation method and centrifugation method. Method: With yield of water extract

retention rates of amygdalin and paeoniflorin as comprehensive evaluation index

orthogonal test was adopted to optimize chitosan flocculant clarification process of Dantao granules with chitosan dosage

flocculation liquid temperature and pH of liquid as factors

three clarification processes including ethanal precipitation method

adsorption clarification technique

high-speed centrifugation method were compared with nature sedimentation. Result: Optimized chitosan flocculant clarification process was as following:added 10% liquid volume of 1% chitosan

pH of liquid 6.0

flocculation liquid temperature 50℃;Water extract amount reduced to around 19%

retention rate of amygdalin and paeoniflorin were more than 89%

it was superior to ethanol precipitation method and centrifugation method. Conclusion: Chitosan flocculant clarification could be used as clarification process of Dantao granules

and this optimized technique was reasonable

stable and feasible for industrial production.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Optimization of Clarification Technology of Yilingjing Oral Liquid

Optimization of Chitosan Flocculation Process for Sangshen Bunao Creams by Orthogonal Test

Preparation of Schisandrae Chinensis Fructus Polysaccharides Microcapsules and Investigation of Its Release Behavior

Optimization of Chitosan Flocculation Process for Sangshen Bunao Creams by Orthogonal Test

Establishment and Evaluation of Mouse Model of Ischemic Heart Disease with Qi and Yin Deficiency Syndrome Based on Proteomics

Related Author

GU Zhi-xin

XIA Xin-hua

ZHU Li

Zhou Fang

XIE An

OU Jin-xiu

ZHANG Ni-yu

CHEN Zhen-gui

Related Institution

Shandong University of Traditional Chinese Medicine,Ji’nan

Shandong Academy of Chinese Medicine,Ji’nan

Natural History Museum of China

Beijing Key Laboratory of Chinese Materia Pharmacology，Institute of Basic Medical Sciences， Xiyuan Hospital，China Academy of Chinese Medical Sciences

Beijing University of Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰