Objective: To observe the curative effect of the Compound Indigoplant oral liquid Solution on children acute upper respiratory infection and evaluate its safety. Method: One hundred and twenty-three children with acute upper respiratory infection were divided into two groups randomly

i e

the treatment group (62 cases

treated with the Compound Indigoplant oral liquid) and control group (61 cases

treated with Ribavirin Spray). Both groups were under conventional therapy. Result: ① The pyretolysis time of treatment group was shorter than control group

(2.8±1.2) d shorter than the control group (3.9±1.1) d

P<0.01.The onset time on pyretolysis of treatment group was earlier than control group

(2.1±1.0) d shorter than the control group (2.9±1.2)d

P<0.01.② The total effective rate on pyretolysis of treatment group 93.5% was higher than control group 85.2%. The total effective rate on pharyngalgia of treatment group 95.2% was higher than control group 80.3%

P<0.05. ③ After treatment for 7 d

the effective rates on symptoms such as cough

nose running and nasal obstruction of treatment group were higher than control group

P<0.05. Conclusion: The Compound Indigoplant oral liquid Solution has rapid onset and high efficacy in treating children with acute upper respiratory infection. Being safe and without any significant side effect

it can be regarded as one of the first choice drugs for children acute upper respiratory infection and has extensive application prospects.