JIAO Ying-hua, XING Lei, TIAN Fa-ming, et al. Clinical Study of Jieju Fushenning in Treatment of Early Type Ⅱ Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 317-320.
DOI:
JIAO Ying-hua, XING Lei, TIAN Fa-ming, et al. Clinical Study of Jieju Fushenning in Treatment of Early Type Ⅱ Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(23): 317-320. DOI: 10.11653/syfj2013230317.
Clinical Study of Jieju Fushenning in Treatment of Early Type Ⅱ Diabetic Nephropathy
Objective: To investigate the clinical efficacy of Jieju Fushenning(JJFSN) in the treatment of early diabetic nephropathy. Method: One hundred and twenty patients with early type Ⅱ DN admitted to our hospital were randomly divided into JJFSN group
Irbesartan group
JJFSN and Irbesartan group
and control group
each group had 30 patients
with 12 weeks as a treatment course.The changes of relevant indicators before and after treatment were observed. Result: In the JJFSN group
the fasting plasma glucose
urinary albumin excretion rate
serum creatinine
glycosylated hemoglobin A1c and other indicators significantly improved.Blood angiotensinⅡ
blood connective tissue growth factor(CTGF)
urinary angiotensin Ⅱ
urinary CTGF significantly reduced.The combined application of JJFSN with Irbersartan had better clinical effect than that of Irbersartan and JJFSN used respectively(P<0.05). Conclusion: Jieju Fushenning is effective in the treatment of early type Ⅱ DN
can delay disease progression and improve patients quality of life
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