Objective: The purpose is to observe the curative effect of Penyanping decoction taken orally with Pudi decoction retention enema treatment on chronic pelvic inflammatory disease(hot and damp stasis junction) and the influence on blood rheological and serum C reactive protein(CRP). Method: One hundred and twenty patients were randomly divided into control group (60 cases) and observation group (60 cases)by numeric table. Patients in control group were given daemonorops margaritae dispersible tablets

4 pieces/time

3 times/day

orally.Take the pills after the menstruation is end

treatment course 20 days;sophora suppository

1 grain/time

1 times/day

after three days from the menstruation is clean

rectal administration

treatment course 10 days.Patients in observation group were given Penyanping decoction

1 dose/day

orally

2 times/day

conventional water frying about 200 mL each time and take it in the morning and evening.Taking it after the menstrual to be clean

treatment course 20 days.Pudi decoction retention enema:1 agent/day

after three days from the menstruation is clean

treatment course 10 days.Observe the both groups for three consecutive menstrual cycle.Record the humid heat and blood stasis syndrome score before and after the treatment.Detect the level of blood rheology indexes and CPR before and after the treatment.Evaluate the patients life quality with the world health organization quality of life measurement profile (WHOQOL-BREF). Result: The total effective rate of observation group on pain reduction index (91.66%) were superior to the control group (78.33%) (P<0.05). The heat and blood stasis syndrome score of observation group is lower than control group(P<0.01)at the fourth

eighth and twelfth week after treatment.The whole blood viscosity

whole blood reductive viscosity(high

medium and low)

red blood cell aggregation index and plasma viscosity got obvious improvement after the treatment(P<0.01).The improvement of the observation group were better than the control group(P<0.01).Serum CRP significantly decreased in observation group is less than control group(P<0.01). The dimension score and total score in life quality

health

daily activities and feel

the observation group is higher than control group(P<0.01). Conclusion: The treatment of Penyanping decoction taken orally with Pudi fang retention enema treatment on chronic pelvic inflammatory disease can improve clinical symptoms and local signs and improve the quality of life of patients

and improve the patient's blood state of thick

sticky

coagulation and sluggish

reduce inflammatory response

improve clinical curative effect

which deserves promoting in the clinical.