Research Situation of Direct Compression Excipients via Co-processing

WANG Song-tao; LIN Xiao; FENG Yi

doi:10.11653/syfj2014040201

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Research Situation of Direct Compression Excipients via Co-processing

更新时间：2024-01-04

- Research Situation of Direct Compression Excipients via Co-processing
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 4, Pages: 201-204(2014)
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- DOI：10.11653/syfj2014040201
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- Published：2014
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WANG Song-tao, LIN Xiao, FENG Yi. Research Situation of Direct Compression Excipients via Co-processing[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(4): 201-204.
DOI：

WANG Song-tao, LIN Xiao, FENG Yi. Research Situation of Direct Compression Excipients via Co-processing[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(4): 201-204. DOI： 10.11653/syfj2014040201.

摘要

直接压片法是片剂生产的首选方法，受粉体流动性、可压性、稀释潜力等性质的影响较大。应用粉体工程学，通过共处理法将单一辅料在颗粒水平上相结合制备的共处理辅料能满足直接压片片剂生产过程对辅料的要求。作者简要介绍了直接压片法的优势、共处理辅料的研究对象、共处理方法，对现有市售共处理辅料进行归纳整理，结合实验室相关研究，展望共处理辅料的应用前景。

Abstract

Direct compression process was the preferred method for preparation of tablets

but itwas highly influenced by powder characteristics such as flowability

compressibility

dilution potential and so on.Demands of excipients in direct compression process could be satisfied by powder engineering with co-processing of single excipient in particles level.This review briefly introduced advantages of direct compression process

choosing object of co-processed excipients and co-processing methods

some of market available co-processed excipients were concluded and analyzed

and combined with laboratory research

application prospect of co-processed excipients was discussed.

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Related Author

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Li-na SHANG

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Di GAO

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Related Institution

Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique， Ministry of Education，Tianjin University of Traditional Chinese Medicine

Institute of Basic Theory of Chinese Medicine, China Academy of Chinese Medical Sciences

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