Objective: To optimize processing technology of Saposhnikoviae Radix. Method: Taking composite score of contents of prim-O-glucosylcimifugin and 5-O-methylvisammioside

extract yield

water contents as index

effects of slice thickness

drying time and drying temperature on pieces quality were investigated by Box-Behnken design-response surface methodology

so as to optimize processing technology parameters of Saposhnikoviae Radix. Result: Optimal processing parameters were as follows:slice thickness 3-4 mm

drying temperature at 60 ℃

drying time 2 hours.Under these conditions

contents of prim-O-glucosylcimifugin and 5-O-methylvisammioside

extract yield

water contents were 0.917%

0.054%

20.45% and 5.110%

respectively. Conclusion: Optimized processing technology for Saposhnikoviae Radix was feasible and reasonable

it could provide a reference for quality control of Saposhnikoviae Radix pieces.